教师基本信息：
职称：杏鑫平台特聘教授
电话：021-31246725
邮箱🚴🏿♀️：huiru_tang（at）fudan.edu.cn (at means @)
地址：杏鑫D105室
个人简介
国家杰出青年科学基金获得者、英国皇家化学会会士、杏鑫平台特聘教授⏳、国家重点研发计划项目首席😺。1986年获西北轻工业杏鑫（现陕西科技大学）学士🥘、1994年获伦敦大学博士学位🥒。1992-2005年先后在英国BBSRC食品研究所、帝国理工杏鑫生物医学部任Senior Scientist等职。2005-2014年先后任中科院武汉物数所研究员、博导、研究部副主任、中科院生物磁共振分析重点实验室创建主任。2014年加盟杏鑫。曾任英国NHS🤱🏽、科技部973及蛋白质重大计划等评审专家🏄🏿♀️、J Proteome Res编委。在Nature及Cell系列、PNAS🦸🏽、J Hepatol、JACS等期刊上发表SCI论文220余篇，被引1.4万余次（H指数~67）🦸🏻。获批发明专利7项。部分工作被Science🪰、Nature等作为“研究亮点”专文评述🤾🏿♂️🛻。现任国际实验核磁共振大会（ENC）执委、中国生物物理学会代谢组学分会会长、自由基生物学及医学分会常务理事，中国抗癌协会肿瘤代谢专委会常务理事，中国营养学会基础营养学分会理事，Metabolomics⛹🏿🛻、Arch Pharm和《基础医学与临床》等编委，Nutrition & Metabolism及Phenomics等副主编。
Personal website: http://www.metabolome.cn/
主要研究方向 (Research Interests)
聚焦代谢物功能及代谢组学30余年，发展高通量超灵敏代谢组学👸🏼、代谢组与转录组/蛋白质组/微生物组数据整合分析等技术，研究重大疾病发生发展及有效干预的分子基础。曾主持国家杰出青年科学基金🎡、国家重点研发计划、国家自然科学基金重大、973课题等项目多项。现承担国家重点研发计划、国家创新群体☂️🤽🏼♂️、上海市级重大专项等任务。
荣誉及获奖情况 (Awards)
英国皇家化学会会士（2005）、国家杰出青年科学基金（2008）、新世纪百千万人才工程国家级人选称号（2009）、王天眷波谱学奖（2010）🥣、武汉市优秀科技工作者（2011）🫱🏼。
代表性通讯作者论文（含共通讯; 一区）
1. J. Xiao, et al, “25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages”, Immunity, 57:1087–1104, 2024
2. Z.L. Wang, et al, “Total synthesis of all stereoisomers of C5-glyceryl-methyl-20-deoxycytidine 5gmC and their occurrence in Chlamydomonas reinhardtii”, Cell Rep Phys Sci, 5:102041, 2024
3. Y.N. Pu, et al, “Gut microbial features and circulating metabolomic signatures of frailty in older adults”, Nat Aging, 4:1249-1262,2004
4. Q.S. Chen, et al, “A novel endogenous retention-index for minimizing retention-time variations in metabolomic analysis with reversed-phase ultrahigh-performance liquid-chromatography and mass spectrometry”, Talanta, 268:125318, 2024.
5. J.X. Zhang, et al, “Simultaneously quantifying hundreds of acylcarnitines in multiple biological matrices within ten minutes using ultrahigh-performance liquid-chromatography and tandem mass spectrometry”, J Pharm Anal, 14:140-148, 2024.
6. C.C. Zhang, et al, “Detecting sub-micromolar analytes in mixtures with a 5-min acquisition on 600 MHz NMR spectrometers”, J Am Chem Soc, 145:25513–25517, 2023
7. Q.Y. Hu, et al, “Reliable quantification of citrate isomers and isobars with direct-infusion tandem mass spectrometry”, Talanta, 259:124477,2023.
8. Y.B. Feng, et al, “Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota”, Nat Microbiol, 7:707-715, 2022.
9. Z.M. Hou, et al, “Inhibiting 3bHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer”, Cell Rep Med, 3:100561, 2022.
10. J.H. Liu, et al, “Simultaneous quantification of 70 elements in biofluids within 5 min using inductively coupled plasma mass spectrometry to reveal elementomic phenotypes of healthy Chinese adults”, Talanta, 238:123720, 2022
11. Q.Y. Hu, et al, “Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry”, Talanta, 238:123059, 2022.
12. M. F. Xia, et al, “Insights into contribution of genetic variants towards the susceptibility of MAFLD revealed by the NMR_based lipoprotein profiling”, https://publons.com/researcher/2776607/huiru-tang/